See below for abstracts for posters and oral presentations for Sweprot 2024.

Posters, sorted by poster board number 

1. Adrián González López, Uppsala University, A putative FusB-type antibiotic resistance operon regulated by a TetR homolog in Streptomyces canus

2. Daniel Larsson, Uppsala University, Structures of ribosomes lacking up to 10 rRNA modification enzymes

3. Derek Logan, Lund University, Structural gymnastics of a bacterial transcription factor: E. coli NrdR

4. Anna Munke, Uppsala University, Structure of a novel virus infecting the marine diatom Chaetoceros tenuissimus

5. Kenta Okamoto, Uppsala University, The emergence of extracellular life in dsRNA viruses

6. Auriane Rakitch, Uppsala University, Structure-functional characterization of a human long non-coding RNA that controls interconnected signalling pathways

7. Shirin Akbar, Uppsala University, Cryo-EM studies of the E. coli rRNA 2’O-ribose methyltransferase RlmE with its native ribosomal substrate

8. Alexandra Berg, Umeå University, Functional annotation of a divergent genome using sequence and structure-based similarity

9. Andrea Cellini, Gothenburg University, Towards structural characterization of a polymodal ion channel

10. Gina Jackisch, Lund University, Structural studies of nucleotide binding and oligomerisation in “stand-alone” ATP-cone domains

11. Juliane John, Stockholm University, Novel variant of the metal free class Ie ribonucleotide reductase

12. Arpitha Kabbinale, University of Gothenburg, Comparing Reduction Rates of ba3 Cytochrome c Oxidase in microcrystals: Insights from serial synchrotron X-ray crystallography using a mixing flowcell

13. Terezia Kovalova, Stockholm University, Structure and function of terminal oxidases from M. smegmatis

14. Ping Li, Lund University, Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism

15. Liubov Makarova, Uppsala University, Unravelling the structural-functional complexity of a conserved long non-coding RNA

16. Spyridoula-Soultana Mitsikosta, Stockholm University, Force-Profile Analysis to study the co-translational folding of Firefly Luciferase

17. Annica Saaret, Stockholm University, IronT – an iron exporter from a thermophile

18. Léon Schierholz, Umeå University, Bioprospecting the Arctic Ocean to investigate enzymatic cold-adaptation

19. Celeste Sele, Lund University, Protein Characterization, Crystallization and Structure Determination at the Lund Protein Production Platform

20. Gabrielle Wehlander, University of Gothenburg, Exploring serial crystallography for capturing Michaelis complexes of a glucuronyl esterase involved in lignocellulose degradation

21. Jacob Whittaker, SLU, Time-resolved Cryo-EM of GltTK – a Glutamate/Aspartate Transporter

22. Joanna Whittaker, University of Groningen, Unravelling the Enigma: 20S Proteasome and VAT ATPase – Partners in a Molecular Dance or Solitary Performers?

23. Malene Wind, University of Copenhagen, Cryo-EM structure of human Aquaporin 8 and a possible non-histidine dependent regulatory mechanism

24. Fan Yang, Uppsala University Structural and functional insights into the ‘giant’ adhesin protein from Apilactobacillus kunkeei

25. Jonatan Johannesson & Emil Sandelin, University of Gothenburg Photocages in time-resolved X-ray studies of non-light responsive proteins 

26. Elham Alzyoud, Karolinska institutet, Distribution and composition of γ-TuRCs during Drosophila spermatogenesis

27. Ying Luo, Linköping University, Direct optimisation of physical parameters in TLS models

28. Dags Macs, Uppsala University, Understanding double arginine’s role in tunnel structure and genome synthesis in dsRNA viruses

29. Petra Meszaros, Uppsala University, Structural basis of photoactivation in phytochromes through time-resolved serial crystallography

30. Szabolcs Bódizs, Uppsala University, Multi-scale time-resolved cryo-EM on a bacterial phytochrome

31. Charles Burridge, University of Gothenburg, Human mitochondrial transcription studied with NMR spectroscopy

32. Lukas Grunewald, Uppsala University, Utrafast Water Rearrangements in Phytochromes: Unveiling a Proton-Coupled Signaling Transduction Mechanism

33. Lucija Ostojic, University of Gothenburg, Time-resolved X-ray solution scattering observations of light induced structural changes in sensory rhodopsin II

34. Thomas Ursby, Lund University, MicroMAX – a beamline with time-resolved macromolecular crystallography capabilities at the MAX IV Laboratory

35. Ylva Strid Holmertz, Linköping University, Statistical Modelling of Heterogeneity in Crystallographic Fragment Screening Data

36. Isabella Andersson Bennig, Lund University, Structural and functional characterization of streptococcal SpnA-host interactions

37. Johanna Gebhard, Uppsala University, Capsid assembly of two algal bloom-regulating viruses

38. Taru Larkiala, Uppsala University, Purification of the native mammalian circadian activator complexes from human cell lines

39. Nicholas DeBouver, Linköping University, Let’s Treat Multi-Dataset Crystallography Data like a Brain

40. Christopher Dirks, Karolinska Institutet/SciLifeLab, Deoxyguanosine analogues allosterically modulate the dNTPase activity of chemoresistance factor SAMHD1

41. Lucas Hultgren, Lund University/SciLifeLab, Crosslinking and Hydrogen/Deuterium Exchange Mass Spectrometry infrastructure service in the ISB platform

42. Deepika Jaiman, Umea University, Comparative Structural-Antibiotic binding Analysis of Lol Proteins in GramNegative Pathogens and Discovery of a LolB-Like Protein in P. gingivalis Using Alphafold

43. Martin Moche, Karolinska Institutet, A national platform for crystallography services

44. Annette Roos, Uppsala University, Scilifelab Drug Discovery and Development Platform – how we can help your idea become a drug

45. Sean  Rudd, Karolinska Institutet, Uncovering pharmacological opportunities to target the drug resistance factor SAMHD1

46. Irwin Selvam, Stockholm University, Investigating phospholipid biosynthesis in Mycobacterium tuberculosis

47. Weixiao Yuan Wahlgren, University of Gothenburg, Chemical Biology and Fragment based screens using solution NMR

48. Lena Lassinantti, Linköping University, Structural Models and Refinement for Multi-Dataset Experiments

49. Hannah Fremlén, University of Gothenburg, Towards Understanding Protein Quality Control of Integral Membrane Proteins by the Bacterial Metalloprotease FtsH

50. Chenyang Guo, University of Copenhagen, Structural characterization of GPR84

51. Zongxin Guo, University of Copenhagen, Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases

52. Surabhi Kokane, Stockholm University, PI-(3,5)P2 mediated oligomerization of the endosomal sodium/proton exchanger NHE9

53. Patric Nordlin, University of Copenhagen, Structural characterization of Human Monocarboxylate Transporters (hMCTs) 

54. Maksim Rulev, Uppsala University, Optimizing IRGM Expression for Structural Characterization

55. Jonas Hyld Steffen, University of Copenhagen, Determinants of cargo specificity in glucosinolate transporters belonging to the nitrate and peptide transport family

56. Justin  Westerfield, Stockholm University, Cotranslational folding of the voltage-gated K+ channel KvAP

57. Malin Bäckström, University of Gothenburg, Protein Production Sweden (PPS)

58. Dilip Badgujar, Uppsala University, Role of Beclin1 in Huntington pathogenesis

59. Filippo Castegnaro, University of Gothenburg, Determination of the Structural and Dynamical Properties of the crucial periplasmic chaperone SurA.

60. Gefei Chen, Uppsala University, Deciphering the structural basis for amyloid secondary nuclea6on

61. Kieran Deane-Alder, Umeå University, Cryo-EM structures of two clinically-relevant glucagon-like peptide 1 missense variants

62. Wolfgang Knecht, Umeå University, Protein production using the Baculovirus Expression Vector System at Lund Protein Production Platform and Protein Production Sweden

63. Ane Metola, Stockholm University, Following the co-translational folding of a multidomain protein

64. Emilia Strandback, Karolinska Institutet, Protein Science Facility, Karolinska Institutet

65. Per Rogne, Umeå University, Direct determination of kinase activity using real-time 31P NMR

66. Emil Stender, Fida Biosystems, Assessing In Solution Binding Kinetics with μL Sample Volume Using Flow-Induced Dispersion Analysis (FIDA)

67. Tobias  Krojer, Lund University, How do Disulfide, Thioacetal and Lanthionine-Bridges influence the Conformations of Macrocyclic Peptides?

68. Morgana Kellogg, Stockholm University, Optimization of the SDD1 Arrest Peptide

69. Juliette Rival, Stockholm University, Novel cancer targets in nucleotide metabolism

70. Raminta Venskutonyte, Lund University, Structural studies of aquaporin inhibition

71. Adams Vallejos, University of Gothenburg, Characterizing protein conformational changes using resampled time-resolved serial X-ray crystallography data

72. Ashish Kawale, University of Gothenburg, Cell-Free Protein Synthesis and In-Cell NMR Platforms at the Swedish NMR Centre

73. Catrine Johansson, Saromics Biostructures AB, An IL-17A crystallization system supporting small molecule structure-based drug design

74. Emma Verver, LUMICKS, Zooming in on dynamic proteins: how the dynamic structure of proteins dictate their function

75. Qingyang Zhang, KTH, Structural Dynamics and the Gating of a large Pore Channel

75. Singh Vishakha, Uppsala University, Structural insights into the characteristic slow translocation in coldadapted bacteria Pseudoalteromonas haloplanktis 

76. Juanita Julsgart, Fidabio, Small molecule interactions with membrane proteins using flow induced dispersion analysis          

Oral presentations        

1. Hannah Osterholz, Uppsala University, Native MS captures LLPS-specific binding of small molecules

2. João Carlos Marcos, University of Minho, Experimental and computational elucidation of the inhibition of myoglobin aggregation by polyethylene glycol

3. Inna Rozman Grinberg, Stockholm University, ATP-cone: evolutionary mobile, structurally conserved domain with different regulatory functions

4. Bozidar Duic, University of Gothenburg, Deciphering the role of HtrA1 in inflammation and neurodegenerative diseases oral presentation

5. Leonardo Monrroy, Uppsala University, Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFEL

6. Wei-Sheng Sun, Umeå University, Breaking Barriers: pCF10 Type 4 Secretion System relies on a self-regulating muramidase to modulate the cell wall

7. Matthias Fink, Karolinska Institutet, The heat shock protein LarA activates the Lon protease in response to proteotoxic stress

8. Shekhar Jadhav, EMBL, Native MS captures LLPS-specific binding of small molecules

9. Maximilian Vieler, Uppsala university, Large-scale profiling E3-ligases reveals substrate binding specificity determinants

10. Jeena Manayath Thekkeyil, Max Planck Institute for Polymer Research, Chaperons-inspired peptide nanofibers interrupt Cu (I) homeostasis in cancer cells

11. Arni Thorlacius, Uppsala university, BAR protein endophilin-B1 displays multiple assembly forms on artificial lipid discs

12. Mia  Abramsson, Karolinska Institutet, Engineering cardiolipin binding to an artificial membrane protein

13. Ved Mehta, Stockholm University, Structure and electromechanical coupling of the sperm specific voltage gated Sodium/Proton exchanger SLC9C1

14. Felipe Otsuka, Lund University, Engineering stereospecificity in glycoside hydrolases through mutagenesis

15. Andreas Dunge, University of Gothenburg/AstraZeneca, Exploring serial crystallography for drug discovery oral presentation

16. Simin Zhang, Karolinska Institutet, Tailor antimetabolite therapy by targeting host nucleos(t)ide kinase and phosphohydrolase

17. Marco Marcia, Uppsala University, Targeting the conserved active site of splicing machines with specific and selective small molecule modulators

18. Viktoria Bågenholm, University of Copenhagen, Inhibition of a muscle chloride channel – structural and functional studies of ClC-1