Download program with abstracts to the oral presentations (PDF)
Friday June 16th
16:30 – 18:00 Conference desk open
18:00 – 19:30 Dinner
19:45 – 21:00 Session Ia: Opening and Awards
Chair: Dr. Knecht & Dr. Burmann
19:45 – 20:15 Welcome, presentation of Keynote Lecturers and the The Svedberg awardee
20:15 – 21:00 The Svedberg Award Lecture: Simon Elsässer (Karolinska Institutet)
21:00 – 22:00 PI meeting
______________________________________
Saturday June 17th
07:00 – 08:45 Breakfast
09:00 – 12:00 Session II: Beyond classical structural biology
Chair: Dr. Neutze
09:00 – 09:45 Keynote 1: Serena DeBeer (MPI Mühlheim, Germany)
Spectroscopic and computational studies of biological nitrogen reduction
09:45 – 10:05 Katja Bekcic (Karolinska Institutet)
Optimizing large-scale production of circular RNA for in-cell NMR of nucleic acids
10:05 – 10:25 Nicolas Pearce (Linköping University)
Refactoring the B-factor: intuitively extracting structural dynamics from
macromolecular disorder
10:25 – 10:50 Coffee
10:50 – 11:35 Keynote 2: Alan Brown (Harvard Medical School, USA)
10:50 – 11:35 Keynote 2: Alan Brown (Harvard Medical School, USA)
Using cryo-EM to build atomic models of ciliary axonemes
11:35 – 11:55 Vajradhar Acharya (University of Gothenburg)
3D TEM Studies of Mammalian Sperm Extra-Axonemal Structures
11:55 – 12:15 Juliane John (Stockholm University)
XFEL investigation of redox-dependant flavin strain in the ribonucleotide reductase
R2b-NrdI complex
12:20 – 13:40 Lunch
Session III: Membrane proteins in health and disease I
Chair: Dr. Esbjörner
13:40 – 14:25 Keynote 3: Layara Akemi Abiko (Biozentrum Basel, Switzerland)
Influencing the β1-adrenergic receptor conformational equilibrium by targeting its
empty cavities
14:25 – 14:45 Yue Chen (KTH Stockholm)
Mechanism of ligand-dependent D2 dopamine receptor activation revealed by freeenergy landscapes
14:45 – 15:05 Jessica Glas (University of Gothenburg)
High-resolution structure of a fish aquaporin reveals a novel extracellular fold
15:05 – 15:25 Lightning talk
15:25 – 16:00 Coffee
Session IV: Membrane proteins in health and disease II
Chair: Dr. Hedfalk
16:00 – 16:45 Keynote 4: Patrick Sexton (Monash University, Australia)
Advancing GPCR drug discovery using cryo-EM
16:45 – 17:05 Nour Aldin Kahllous (Uppsala University)
Design of drug efficacy guided by free energy simulations of G protein-coupled
receptors
17:05 – 17:25 Alexandra Berg (Umeå University)
Nematocida displodere mechanosensitive ion channel of small conductance 2
assembles into a unique six-channel super-structure in vitro
17:25 – 17:45 Johannes Thoma (University of Gothenburg)
Exploiting OMVs for the in-situ characterization of bacterial envelope proteins
18:00 – 19:30 Dinner
20:00 – 21:30 Poster Session II
______________________________________
Sunday June 18th
07:00 – 08:45 Breakfast
Session Ib: Awards
Chair: Dr. Morud Lekholm
09:00 – 09:15 Presentation of The Theorell Awardee.
09:15 – 10:00 The Theorell Award Lecture: Marta Carrroni (SciLifeLab Stockholm)
10:00 – 10:30 Coffee
Session V: Integrated structural biology
Chair: Dr. Burmann
10:30 – 11:15 Keynote 5: Sebastian Hiller (Biozentrum Basel, Switzerland)
Integrative structural biology to resolve molecular machines and membrane
megaprores
11:15 – 11:35 Annika Breidenstein (Umeå University)
Structural and functional characterization of the relaxase TraI – Implications for
Gram-negative Type 4 secretion systems
11:35 – 11:55 Vamsi Krishna Moparthi (Linköping University)
Regulation of MYC-MAX DNA binding in cancer
11:55 – 12:15 Oksana Koshla (Uppsala University)
The iron sensing transcriptional factor IdeR and its function in the metabolism of
Saccharopolyspora erythraea
12:20 – 13:40 Lunch
Session VI: Success stories using research infrastructures in Sweden
Chair: Dr. Göran Karlsson
13:40 – 14:00 Bärbel Lorenz (Lumicks)
Molecular tractor beams? Unravelling biological mechanisms by looking at single
molecules in real-time
14:00 – 14:20 Simon Ekström (Lund University)
Cross-linking and Hydrogen-Deuterium Exchange Mass Spectrometry as a National
Infrastructure Service
14:20 – 14:40 Huanbing Wang (Stockholm University/China)
The structural biology in protein folding and aggregation.
14:40 – 15:00 Atsarina Larasati Anindiya (University of Gothenburg)
Prediction of peptide binding to survivin based on experimental microarray
fluorescence intensities.
15:20 – 15:40 Tristan Kenney (Linköping University/University of Toronto)
The dynamic interactions between Myc and RNA Polymerase II component TFIIF
component
15:40 – 16:10 Coffee
16:20 – 18:00 Annual football match
18:00 – 19:30 Dinner
20:00 – 21:30 Poster Session II
______________________________________
Monday 19th June
07:00 – 08:45 Breakfast
Session VII: Drug discovery
Chair: Dr. Käck
09:00 – 09:45 Keynote 6: Alessio Ciulli (University of Dundee, UK)
How PROTAC degraders work: Molecular recognition and design principles
09:45 – 10:05 Wolfgang Knecht (Lund University)
Structural basis for small molecule binding to SARS-COV-2 nonstructural protein 10
10:10 – 10:30 Coffee
10:30 – 10:50 Andreas Luttens (Uppsala University)
Virtual Fragment Screening for DNA Repair Inhibitors in Vast Chemical Space
10:50 – 11:10 Adrian Gonzales Lopez (Uppsala University)
Cryo-EM structures of Staphylococcus aureus 70S ribosomes in complex with
elongation factor G and fusidic acid
11:10 – 11:30 Sayyed Jalil Mahdizadeh (University of Gothenburg)
I-TripleD, an AI tool for de novo drug discovery
11:35 – 11:50 Closing of meeting and award of prizes for best presentation and poster
12:00 – 13:00 Lunch + Departure