Program Sweprot 2026:

Friday June 12th

16:30 – 18:00 Conference desk open

18:00 – 19:30 Dinner

19:45 – 20:45  Session I: Opening and Award

Chair: Profs. Anders Liljas, Elisabeth Sauer-Eriksson, Ronnie Berntsson

19:45 – 20:00 Welcome, presentation of the Svedberg award

20:00 – 20:45 The 2026 Svedberg Award Lecture by Dr. Nils Landgren, Uppsala University. 

Weighing in: What native mass spectrometry can tell us about elusive protein interactions

20:45 – 21:15 PI meeting

Saturday June 13

07:00 – 08:45 Breakfast

09:00 – 11:40 Session II: Multiscale biology

Chair: Prof. Elisabeth Sauer-Eriksson

09:00 – 09:45 Keynote 1: Prof. Mathias Uhlén, KTH Royal Institute of Technology, Sweden

The Human Protein Atlas journey – towards AI-based precision and translational medicine

09:50 – 10:10 Nicholas Valerie, Karolinska Institute

Targeted protein degradation reveals a cryptic NUDT5–PPAT axis governing nucleoside analog drug efficacy

10:15 – 10:35 Simin Zhang, Karolinska Institute

Novel roles of NUDT15 in antileukemic therapies

10:35 – 11:05 Coffee

11:05 – 11:25 Candice Gautier, Uppsala University

Divide to conquer: Deciphering the interaction landscape of whirlin, an Usher syndrome protein.

11:30 – 11:50 Abi Ghifari, University of Gothenburg

Structural and molecular basis of protein quality control in the inner mitochondrial membrane by the prohibitin-mAAA complex

12:00 – 13:30 Lunch

13:30 – 17:20 Session III: Structural enzymology

Chair: Prof. Uwe Sauer

13:30 – 14:15 Keynote 2: Prof. Anne Bertolotti, MRC Laboratory of Molecular Biology, UK

The integrated stress response: From the bench to the clinic and back.

14:20 – 14:40 Lukas Grunewald, Uppsala University

Shining Light on Phytochromes: Ultrafast Photosignalling Captured by Time-Resolved Serial Crystallography

14:45 – 15:05 Shirin Akbat, Uppsala University

Cryo-EM reconstruction of the 23S rRNA 2′-O-methyltransferase RlmE in complex with its ribosomal substrate reveals structural basis of late 50S maturation

15:10 – 15:30 Gabrielle Wehlander, Gothenburg University

Structural investigation of the reaction mechanism of a glucuronyl esterase using time-resolved serial crystallography

15:30 – 16:10 Coffee

16:10 – 16:40 Johannes Messinger, Umeå University

Atomic resolution structure of spinach rubisco reveals protons and dynamics

16:45 – 17:05 Johan Glerup, Gothenburg University

Time-resolved studies of nitric oxide turnover in cytochrome c oxidase

18:00 – 19:30 Dinner

20:00 – 21:30 Poster Session I

Sunday June 14

07:00 – 08:45 Breakfast

09:00 – 10:00 Session IV: Host-pathogen interactions

Chair: Prof. Erik Johansson

09:00 – 09:45 Keynote 3: Prof. Lars-Anders Carlson, Umeå University, Sweden

Replication of arthropod-borne viruses through the lens of a cryo-electron microscope

09:50 – 10:10 Rupesh Balaji Jayachandran, Umeå University

Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access

10:10 – 10:30 Josy ter Beek, Umeå University

Pili are essential for conjugation also in many Gram-positive bacteria

10:30 – 11:00 Coffee

11.00 – 14.05 Session V: Integrated structural biology

Chair: Prof. Lars-Anders Carlsson

11:00 – 11:45 Keynote 4: Prof. Martin Beck, Max Planck Institute of Biophysics, Frankfurt, Germany

From interactomes to in situ structures: what proteomics adds to structural biology

11:50 – 12:10 Yat Kei Lo, Uppsala University

Structural basis of a novel PMF-coupled carbon-concentrating mechanism

12:10 – 13:20 Lunch

13:20 – 13:40 Agnes Moe, University of Bern, Switzerland

Molecular architecture of lipid transfer between the two mitochondrial membranes

13:45 – 14:05 Justin Westerfield, Stockholm University,

Cotranslational Folding and “Constrained Monomers” in the Maturation of HIV-1 Protease

14:10 – 16:00 Session VI: Folding and misfolding

Chair: Prof. Ronnie Berntsson

14:10 – 14:55 Keynote 5: Prof. Patrick van der Wel, University of Groningen, Netherlands

Dissecting and modulating pathogenic aggregation pathways of the atypical amyloidogenic protein mutated in Huntington’s disease

15:00 – 15:20 Caroline Körösy, Utrecht University, the Netherlands

Accessing the Low-Force Regime: Magnetic Tweezers Reveal Early Activation Steps in von Willebrand Factor

15:25 – 15:45 Morgana Kellog, Stockholm University

CryoEM of a Variant of the SDD1 Arrest Peptide Reveals the Mechanism of Enhanced Arrest

15:50 – 16:20 Coffee

16.20 – 18:00 Networking / games

18:00 – 19:30 Dinner

20:00 – 21:30 Poster Session II

Monday 15th June

07:00 – 08:45 Breakfast

09:00 – 11:50 Session VII: Hot topics

Chair: Prof. Linda Sandblad

09:00 – 09:45 Keynote 6. Dr. Tzviya Zeev Ben Mordehai, Utrecht University, Netherlands

Cryo-EM single particle analysis meets cryo-ET at the sperm tail

09:50 – 10:10 Samuel Hjorth-Jensen, Lund University

Structural insights into the Danio rerio aquaglyceroporin 3b

10:15 – 10:35 Jakob Merlin Silberberg, Stockholm University

Redox-sensitive Regulation of the K+ efflux system KefC by Glutathione and NADH

10:35 – 10:55 Coffee

10:55 – 11:15 Sergio Trillo-Muyo, Gothenburg University

Cryo-EM structure of CLCA1 identifies CLCA1 as a founding member of a novel metzincin family

11:20 – 11:50 Closing of meeting and award of prizes for best presentation and poster

12:00 – 13:00 Lunch + Departure